by Dr. Martina Schneider
In order to keep up with technical progress and reduce the need for animal testing, the EU has been adopting the harmonised and internationally agreed test guidelines published by the Organisation for Economic Cooperation and Development (OECD) via Regulation (EC) No 440/2008. This regulation covers the test methods required to determine the physicochemical, toxicological and ecotoxicological properties of chemicals under REACH (Regulation (EC) No 1907/2006).
The recently published Commission Regulation (EU) 2019/1390 amends the annex to Regulation (EC) No 440/2008. Two new test methods for the assessment of ecotoxicity and nine new test methods to determine human toxicity were added. Seven existing test methods were updated. The main endpoints affected, with 11 out of the 18 tests under consideration, are skin and eye irritation/corrosion, skin sensitisation, genetic toxicity and endocrine disrupting effects.
The new test methods come into force on October 16th 2019 and are designed for registrants who are deciding on their testing strategies for their applications. It is not mandatory to re-test existing registered end-points, unless requested to do so by ECHA.
Commission Regulation (EU) 2019/1390
- Test methods
- European Union
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