U.S. EPA Designates Low-Priority Substances

Posted on: March 6, 2020

by John J. photo of flasks - Learn more about the recent EPA ruling on Low Priority SubstancesKowalski, CHMM

On February 26, 2020, the U.S. Environmental Protection Agency

(EPA or the Agency) published a notice designating 20 chemical substances as Low-Priority Substances under Section 6(b) of the Toxic Substances Control Act (TSCA), as amended.  EPA’s designation of a substance as a Low-Priority Substance indicates that the Agency has concluded that a risk evaluation of the substance is not warranted at this time.

The 20 chemical substances designated as Low-Priority Substances are listed in the table below.

CAS RN Chemical Name
4435-53-4 1-Butanol, 3-methoxy-, 1-acetate
31138-65-5 D-gluco-Heptonic acid, sodium salt (1:1), (2.xi.)-
526-95-4 D-Gluconic acid
299-28-5 D-Gluconic acid, calcium salt (2:1)
90-80-2 D-Gluconic acid, .delta.-lactone
299-27-4 D-Gluconic acid, potassium salt (1:1)
527-07-1 D-Gluconic acid, sodium salt (1:1)
109-43-3 Decanedioic acid, 1,10-dibutyl ester
661-19-8 1-Docosanol
629-96-9 1-Eicosanol
6920-22-5 1,2-Hexanediol
112-92-5 1-Octadecanol
55934-93-5 Propanol, [2-(2-butoxymethylethoxy)methylethoxy]-
105-53-3 Propanedioic acid, 1,3-diethyl ester
108-59-8 Propanedioic acid, 1,3-dimethyl ester
88917-22-0 Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate
24800-44-0 Propanol, [(1-methyl-1,2-ethanediyl)bis(oxy)]bis-
110-98-5 2-Propanol, 1,1′-oxybis-
25265-71-8 Propanol, oxybis-
111-01-3 Tetracosane, 2,6,10,15,19,23-hexamethyl-

These chemical substances are also listed on EPA’s Safer Chemical Ingredients List.

Recommended Action Item

Continue to watch this space, as we frequently post articles regarding significant developments under TSCA.


Environmental Protection Agency.  “Final Designation of Low-Priority Substances Under the Toxic Substances Control Act (TSCA); Notice of Availability”  Federal Register 85 (26 February 2020): 11069-11079.


United States



Low-Priority Substances

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